Humankind is facing a perfect storm of climate change, biodiversity loss, and multiple forms of malnutrition (stunting, wasting, micronutrient deficiencies, and obesity) coexisting in the same country, community, household, and even individual. Challenges from each of these areas are well known and recognized, but what seems to be missing in many development and policy circles is a recognition that food is at the centre of all three of these issues. This paper identifies entry points within agri-food systems to improve biodiversity and diets, two levers that can be used to enhance nutrition and optimize environmental sustainability while ensuring social equity, especially of the most vulnerable people. It also presents recommendations for concrete actions by key stakeholders – governments, academia, civil society, private sector, and development partners –to build resilient, inclusive, and sustainable agri-food systems.